Cancer Questions

MCQs Cancer:

1. Which is least likely to occur for removal of cancer cells?

a) Phagocytosis
b) complement fixation
c) T-cell based cytotoxicity
d) autophagy

2. p53 protein is associated with all of the following except

a) tumor suppression                                                                                                    
b) programmed cell death                                                                                c)transcription                                                                                                                              
d)post- transcription modifications

3. Proto-oncogenes are                                                                                            

a) oncogenes found in transforming retroviruses

b) oncogenes present in protozoa                                                                             
c) genes encoding oncogenes related proteins in extinct organisms                              
d) cellular genes encoding proteins related to viral oncogenes

4.The normal cellular counterparts of oncogenes are important for the following functions excepts                                                                                                        
a) promotion of cell  cycle progression                                                                     
b) inhibition of apoptosis                                                                                            
c) promotion of  DNA repair                                                                                    
d) Promotion of nuclear transcription 

5. Which of the following is not a property of cancer cells?                                 
a) Lack of density dependent inhibition of cell proliferation                         

b) loss of contact inhibition of  movement                                              

c) fail to undergo apoptosis

d) increased requirement of extra cellular growth factors

6.One difference between a cancer cell and a normal cell is that                         
 a) the cancer cell is unable to synthesize DNA                                                           
 b) the cell cycle of the cancer cell is arrested at the S phase                               

c) cancer cells continue to divide even when they are tightly packed                                
d) cancer cells cannot function properly because they suffer from density-dependent inhibition

Answer:

1. d) autophagy

2. d) post- transcription modifications

3. d) cellular genes encoding proteins related to viral oncogenes

4. c) promotion of  DNA repair   

5. d) increased requirement of extra cellular growth factors

6. c) cancer cells continue to divide even when they are tightly packed       

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