1.Which of the
following period corresponds to temperature fall and a cold and dry climate on
earth for the first time?
(1) Ordovician period
(2) Silurian period
(3) Carboniferous period
(4) Devonian period
2.In which of the
following molecular markers, gel electrophoresis is not required
(1) VNTR
(2) RAPD
(3) SNP
(4) None
3.Match the
following products with the microbes which produce them on large scale and find
the correct combination
Product Microbe
(P) Lysine — Brevibacterium spp.
(Q) Glutamic acid — Corynebacterium
glutamicum
(R) Gibbellic acid — Fusarium
mohiliforme
(S) Riboflavin — Eremothecium
ashbyi
(1) Q, R
(2) P, Q
(3) R, S
(4) R, S
4.Pure water does
not conduct electricity be cause it
(1 ) Has low boiling water
(2 ) Is almost unionised
(3 ) Is neutral
(4 ) Is readily decomposed
5.A radiolabelled
Co2 will release in which of the following case
(1) When acetyl Co-A entering
Kreb cycle has radio labelled
(2) Glycine entering glycine
decarboxylase system has radiolabelled a C
(3) Glycine entering glycine
decorboxylase system has radiolabelled C at the coo-group
(4) When g’ (gamma) c of acetoacetate is
radiolabelled during formation of ketone bodies
6.Choose the
mismatch.
(1) Rotenone –– inhibits the
transfer of electron the NADH–CoQ reductare
(2) Piericidin A –– Compete with
Cyt (a.a3).
(3) Antimycin A –– block electron
transport at the level of complex III.
(4) Cyanide –– binds with cytochrome oxidase complex
7.Amino acid
residues present in silk fibroin, permitting a close packing of b sheets and an
interlocking arrangement of R groups?
(1) Gly, Val
(2) Leu, Arg
(3) Ala, Gly
(4) Gly, His
8. Gene for an
enzyme which catalysis synthesis of a secondary metabolite in an angiosperm was
transferred to a bacterial expression vector. But it was found that transgene
was expressed but a functional enzyme was not synthesized which could be the
best possible explanation?
(1) Plant enzyme was not stable
in bacteria
(2) Post translational
modification did not occur
(3) The promoter used were not
appropriate
(4) Both B and C
9. The “Master
Regulatory Gene” is located on which chromosomes in humans? (1) x chromosome
(2) Y chromosome
(3) Both X, Y chromosome
(4) Autosomes
10. In which of the following combination the
name of hormone, its chemical type & its tissue of origin correctly
matched?
(1) Aldosterone, Peptide,
Pancreas
(2) Glucagon, peptide, cortex
Adrenal
(3) ACTH, peptide, adrenal cortex
(4) Vasopressin, Peptide, posterior pituitary
Answers:
1. (4) Temperature
fall and a cold and dry climate on earth for the first time corresponds to
devonian period.
2. (3) SNP
are described as the third generation molecular marker. In RAPD, VNTR gel-based
assay are necessary that are time consuming. Single nucleotide polymorphisms
(SNPs) represent sites, where DNA sequences differs by a single base. Several
non-gel based methods are available for SNP detectio
3.
(3) Correct
combination
Glutamic acid –– Corynebacterium
glutamicum.
Riboflavin –– Eremothecium ashbyi.
4.
(2) Pure
water does not conduct electricity because it is almost unionised.
5. (3) A
radiolabelled CO2 will release if glycine has radiolabelled C at the – COO¯
group enter into glycine decarboxylase system because during decarboxylation
CO2 is released from carboxylic group of glycine.
6.
(2) Piericidin A
competes with Q (ubiquinone) and blocks the transfer of electrons at the
NADH-CoQ reductase complex
7.
(3) Silk fibrion is
rich in Ala and Gly residues, permitting a close packing of b sheets and an
interlocking arrangements of R groups
8.
(2) Transegene was
expressed but a functional enzyme was not synthesized which means post translational
modification did not occur in the products encoded by transcend.
9.
(1) The “master
Regulatory gene “ is located on Y chromosome in humans, Sex determining region,
Y (SRY) gene is the only gene on Y chromosome that is necessary to initiate
testies development.
10.
(4) Vasopressin also
known as anti-diuretic hormone is a peptide hormone which is secreted from posterior
pituitary
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